Telomere Length Measurement for Human Cervical Epithelial Cells

The cervical epithelial cells in the cervix have structural integrity and restrict the entry of molecular and cellular material into the cervix. Human cervical epithelial cells can serve as a useful in vitro model for the study of cervical-related pathophysiology. CD BioSciences can provide telomere length measurement of cervical epithelial cells, which can be used to explore the correlation between telomeres and cervical-related diseases.

Telomere Length Changes in Cervical Epithelial Cells

The cervix is the lower part of the uterus that functions to promote fertility and protect the female reproductive tract and fetus from potential pathogens. Human cervical epithelial cells isolated from the human uterus are squamous in shape.

Each division of cervical epithelial cells reduces telomere length, resulting in apoptosis or senescence. When atypical conditions lead to a reduction in telomere length, it leads to an increased level of instability in the cellular genome. This may be the main triggering event leading to many cervical diseases.

Sample Requirements

We provide telomere length measurement solutions for cervical epithelial cells. The specific requirements are as follows. If you need the remaining samples after the test is completed, we will return the samples.

• Sample type. We can receive cell samples from you or genomic DNA samples extracted from cells.
• Sample quantity. Each collection tube contains > 10⁶ cells, and DNA samples > 1 μg.
• Shipping requirements. We recommend dry ice transport. We will use the cells or DNA for experiments directly and immediately upon receipt.

Our Services of Cervical Epithelial Cell Telomere Length Measurements

We can provide our clients with the required telomere length data for cervical epithelial cells. We implement the most important steps, including a comprehensive assessment of the study question, sample type, analysis time, and available resources, to select the most appropriate available measurement method. Further, a more robust study design can address the challenges of longitudinal studies with samples over time.

• Measurement methods
  Our researchers are very familiar with the methodological nuances of the various procedures used to measure telomere length, including TRF, qPCR, Q-FISH, and more. This will ensure that we can select the best evaluation method to meet the needs of our clients' study designs.

• Telomere length measurement
  We measure telomere length with other measurement services, including the generation of relative telomere length and average telomere length per telomere, telomere length variation, short telomere frequency, and long telomere frequency.

Applications of Cervical Epithelial Cell Telomere Length Measurements in Aging Studies

• By measuring telomere length, we can gain insight into the role of shortened telomeres in the development and progression of aging-related diseases such as cervical cancer.
• Our measurement of telomere length in cervical epithelial cells can be used in longitudinal studies to track age-related changes and to assess the impact of lifestyle, environmental factors, and medical interventions on cervical aging.
• Our analysis of cervical epithelial cell telomere length contributes to research in the field of biogerontology, providing data on the cellular aging process specific to cervical tissue and its correlation with overall aging and health.

CD BioSciences is a biotechnology company that offers a variety of telomere analysis technologies. We help scientists or pharmaceutical companies measure telomere length to reveal important information about aging or age-related diseases. If you need telomere length measurement of cervical epithelial cells or other samples, please contact us to learn more.

Reference

1. Albosale AH and Mashkina EV. Association of Relative Telomere Length and Risk of High Human Papillomavirus Load in Cervical Epithelial Cells. Balkan J Med Genet, 2022, 24 (2): 65-70.