Targeted RNA sequencing can help us select specific transcripts for accurate characterization and quantification. This highly accurate approach is achieved by either enrichment or amplicon methods, both of which enable us to perform expression analysis of aging genes of interest.
Supported by CD BioSciences' technology platform, our targeted transcriptome sequencing service provides genomic and gene expression information analysis of specific genomic regions to help understand aging mechanisms and age-related disease processes in a highly sensitive and cost-effective manner.
Overview of Targeted Aging-Related Transcriptome Analysis Services
Customized transcriptome profiling
We offer customized transcriptome profiling services tailored specifically to aging research. This involves the analysis of gene expression patterns in various tissue types or cell cultures relevant to aging, such as brain, muscle, or blood samples.
Differential gene expression and network analysis
We perform differential gene expression analysis to identify genes that are differentially expressed between young and old samples or between healthy and diseased states associated with aging. Further, we employ network analysis techniques to identify interactions between gene regulatory networks and differentially expressed genes. This analysis will help identify key genes and pathways involved in the aging process.
Pathway and functional analysis
We conduct pathway and functional analysis to investigate the biological pathways and processes that are significantly enriched among the differentially expressed genes, to help our clients gain insight into the molecular mechanisms of aging and age-related diseases.
Our Workflow of Targeted Aging-Related Transcriptome
We use state-of-the-art sequencing platforms to sequence target samples. In addition to our extensive experience and robust sequencing technology, we also offer sequencing services that meet a wide range of research objectives.
- RNA sequencing library preparation
Our library preparation solution for targeted RNA sequencing provides insight into many aging-associated transcripts through a rapid workflow that includes rRNA removal and cDNA reverse transcription formation.
- RNA sequencing
We provide high-throughput, high-accuracy, low-volume RNA sample input sequencing, offering flexible solutions for RNA quantification, differential gene expression, de novo transcript annotation, and other potential sequencing services.
- Bioinformatics analysis
Through data analysis, we can obtain individual genes or lists of genes associated with annotated data on aging pathways, diseases, tissues, etc. to support researchers in identifying aging and disease mechanisms, drug targets, and biomarkers.
Our Sequencing and Analysis Capabilities
In the table below, we list our sequencing capabilities and data analysis capabilities for reference. Our analysis capabilities include but are not limited to these. If you need more details, please contact us with your customized requirements.
| Sequencing platforms |
Data analysis |
- Single- or double-end sequencing, with optional reads depending on study objectives
- Suitable for targeted or small genome sequencing in any laboratory
- Compare sequencing platforms and determine the best system for your research project
- Tailor-made sequencing reagents
|
- Functional enrichment analysis
- Transcription factor and senescence gene functional annotation
- Novel transcript identification
- Gene expression quantification
- Differential expression profiling
|
Advantages of Targeted Transcriptome Sequencing
- A highly accurate method to measure specific transcriptomes to obtain qualitative and quantitative information.
- Gene expression can be analyzed in a wide dynamic range.
- Compatible with many sample types, including low-quality, formalin-fixed, and paraffin-embedded RNA.
- Simple workflow and high-throughput, fast gene expression analysis.
- High-quality, publishable data to support research.
- Provide valuable information about changes in gene expression in aging.
CD BioSciences has gained extensive experience in providing targeted sequencing services for aging clients worldwide and can provide comprehensive information in a time-saving manner. We provide a one-stop solution from project consultation to sequencing analysis and are confident that we can provide the best service to our clients at the most competitive cost. If you are interested in our services, please feel free to contact us or make an online inquiry.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
