In recent years, immune-based approaches have emerged as powerful tools for discovering aging-related biomarkers. By studying the immune system, researchers can identify immune markers and pathways associated with aging and age-related diseases. CD BioSciences provides immunome-based discovery of aging-related biomarkers committed to advancing our understanding of the aging process and developing healthy aging interventions.
Overview of Our Aging-Related Biomarker Discovery Services
Based on our immune profiling techniques, such as flow cytometry, mass cytometry (CyTOF), or single-cell RNA sequencing (scRNA-seq), we facilitate the discovery of immune-based biomarkers associated with aging, for early detection, prognosis, and monitoring of age-related diseases.
Our Workflow of Aging-Related Biomarker Discovery
CD BioSciences employs a systematic workflow to discover biomarkers associated with aging using immunoassay technology. Our workflow includes the following key steps.
- Study design and sample collection
We work closely with researchers to design studies that address their specific research objectives. We assist in collecting samples from longevity cohorts, different age groups, or aging animal models.
- Sample processing and immune profiling
We perform sample processing, including tissue sample preparation and immune cell isolation. We then apply our advanced immune profiling techniques, such as flow cytometry, CyTOF, or scRNA-seq, to analyze the immune cells and generate high-quality data.
- Immunome-based aging-related biomarker identification
Our team of bioinformatics experts analyzes the immune profiling data using advanced algorithms and statistical methods. We identify aging-related biomarkers by assessing changes in immune cell populations, phenotypes, functional properties, and gene expression patterns.
- Validation and functional studies
Identified biomarkers are further validated using additional techniques, such as Western blotting or quantitative PCR, to confirm their expression patterns and assess their functional significance. Functional studies may involve in vitro or in vivo experiments to investigate the role of the biomarkers in aging or age-related diseases.
- Data interpretation and reporting
We offer comprehensive reports to our clients, including identified aging-related biomarkers, their relevance to the study objectives, and recommendations for further investigation.
Applications of Aging-Related Biomarker Discovery
Longevity mechanism research
Our identified aging-related biomarkers through immune profiling can provide valuable insights into the underlying processes that contribute to aging. Moreover, these biomarkers can be used to study the effects of various interventions and lifestyle factors on aging and longevity.
Disease prevention and early detection
We utilize aging-related biomarkers as predictive indicators of disease risk and progression. By identifying biomarkers associated with age-related diseases, such as cardiovascular disease, neurodegenerative disorders, and cancer, preventive interventions can be developed to delay or mitigate the onset of these diseases. Additionally, biomarkers can be used for early detection and diagnosis, enabling timely interventions and improved patient outcomes.
Drug development
By identifying specific immune markers or pathways that are dysregulated during aging, we can design interventions that specifically target these processes. This will allow the development of novel drugs or repurposing of existing drugs to modulate the immune system.
By employing a systematic workflow to discover biomarkers, CD BioSciences enables our clients to uncover novel biomarkers associated with aging and age-related diseases, contributing to the development of early detection and drug development. If you are interested in our services, please feel free to contact us or make an online inquiry.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
