DNA methylation changes can be used as a biomarker of aging because its abnormal age-dependent changes are a potential cause of the aging process and the development of age-related diseases. Several interventions have been demonstrated to prevent age-related diseases and extend lifespan, including dietary, pharmacological, and genetic, and most of the changes are associated with age-related DNA methylation changes.
To better understand the effects and molecular mechanisms of interventions for aging and longevity, CD BioSciences can provide services to evaluate longevity interventions using DNA methylation technology.
Types of Longevity Interventions We Can Evaluate
Longevity is mainly influenced by genetic, epigenetic, and environmental factors, and interventions in these pathways can be used to achieve lifespan extension. For various interventions, we offer evaluation services of the efficacy of aging-delaying interventions through rigorous outcome measures using DNA methylation to verify whether they can extend lifespan.
Evaluation of the Effects of Dietary Interventions on Longevity Using DNA Methylation
We provide evaluation services of dietary interventions to prevent aging and prolong life, exploring the specific utility and mechanisms of various nutrients and caloric intake. The study is primarily using animal models and all animal experiments comply with all regulations. We can customize protocols for different nutrient or calorie-restricted studies, including folic acid, vitamin B12, niacin, vitamin E, retinol, calcium, etc.
Evaluation of the Effects of Pharmaceutical Interventions on Longevity Using DNA Methylation
CD BioSciences specializes in evaluating the effects of a broad spectrum of pharmacological interventions on longevity with DNA methylation analysis. Our expertise extends to conducting in vitro and in vivo studies for evaluation services. From small molecules targeting specific epigenetic modifiers to novel biologics designed to modulate chromatin structure, we assess a wide range of interventions.
Evaluation of the Effects of Genetic Interventions on Longevity Using DNA Methylation
CD BioSciences provides genetic intervention evaluation services using DNA methylation analysis. We assess the impact of gene editing techniques such as CRISPR-Cas9 and TALENs on DNA methylation patterns. Our services also include evaluating gene silencing approaches, such as RNA interference (RNAi) and antisense oligonucleotides, to determine their effect on DNA methylation.
Our Advantages
- Use of animal models associated with human aging and disease.
- Quality control to ensure data quality for each sample.
- Comprehensive bioinformatics analysis and publishable data.
- Robust and accurate DNA methylation analysis.
- One-stop service from initial experimental design to complete evaluation.
CD BioSciences has years of experience in providing DNA methylation analysis services and a unique technology platform that can help you address possible barriers and challenges in your research and assist you in evaluating an innovative approach to longevity interventions.
We are committed to providing a one-stop service for evaluating longevity interventions using DNA methylation technology for our clients around the world. Please feel free to visit and contact us to discuss how we can help you develop relevant DNA methylation clocks and conduct evaluations of longevity interventions.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
