Although the specific mechanisms of human aging are still not fully explored, whole-transcriptome sequencing provides a wide range of transcriptome analysis to aid in-depth analysis of aging-related gene expression. CD BioSciences provides transcriptome sequencing services tailored to your research objectives for your aging samples, including a one-stop sequencing service from sample preparation to data analysis, enabling rapid analysis and insight into the RNA of your target subjects.
What is Whole Transcriptome Sequencing?
It is an important tool for addressing the molecular mechanisms of biological and medical problems, which can reveal the presence and amount of RNA in biological samples. Whole transcriptome sequencing analysis can include the analysis of coding and non-coding RNAs such as mRNA, lncRNA, miRNA, and circRNA for a comprehensive transcriptional regulatory networks analysis.
Therefore, CD BioSciences performs whole transcriptome sequencing of aging to understand all the transcriptional activities associated with aging, to demonstrate the dynamics of RNAs at different genomic levels with age, and to provide the possibility of discovering age-associated RNA candidate genes.
Whole Transcriptome Sequencing Applications in Aging Research
- We analyze mRNA, ncRNA, and miRNA in a single sequencing, to explore the regulatory elements associated with aging.
- We also decipher the role of RNA in aging and discover relevant RNA mechanisms that can help develop anti-aging drugs or treat related diseases.
Our Services of Aging Whole Transcriptome Sequencing
We provide a full suite of transcriptome sequencing services for aging research, including library preparation, high-throughput sequencing, and bioinformatics analysis. To gain a comprehensive understanding of aging-related mechanisms, our researchers can obtain high-quality aging analysis services through whole-transcriptome sequencing.
After you submit your samples, we will help you with sample quality control to ensure that the samples meet technical standards. Following our service process, RNA libraries, both coding and non-coding, are prepared based on your target organisms, followed by sequencing with the appropriate sequencing instrument and sequencing system, with all sequencing reagents provided by us on a custom basis. The final result data will be quality-controlled for quality assurance and bioinformatically analyzed to provide publishable results.
Our Sample Requirements
| Sample types |
Amount |
Concentration |
Storage |
| Total RNA (Acceptable for blood, cells, and tissues) |
≥ 5 mg |
≥ 20 μg/μL |
RNA should be stored in nuclease-free water or RNA stabilization solution. |
Advantages of Our Services
- Allows for non-coding RNA and splice variant detection/comparison across phenotypes.
- Ability to quantify entire gene levels or to quantify individual transcripts.
- The detection range and sensitivity can help find more of the data being sought.
- Multiple sample types are suitable, and fast turnaround time, and high-quality sequencing data.
Whole transcriptome sequencing is very important to understand the expression of aging genes and the mechanisms of related diseases. As one of the few professional aging research service providers, CD BioSciences provides one-stop aging transcriptome sequencing services with years of service experience and a technology platform. If you are interested in our services, please feel free to contact us or make an online inquiry.
Reference
- Kukurba KR, Montgomery SB. RNA Sequencing and Analysis. Cold Spring Harbor Protocols, 2015, 11: 951.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
