Developing anti-aging drugs involves intricate interactions within biological systems, necessitating a thorough understanding of how these drugs behave in the body. Pharmacokinetics (PK) is the branch of pharmacology that focuses on drug absorption, distribution, metabolism, and excretion (ADME). The insights gained from pharmacokinetic studies allow researchers to optimize drug formulation, dosing regimens, and therapeutic strategies, ultimately leading to more effective and safer products. CD BioSciences offers expert pharmacokinetic services through in vitro and in vivo methodologies to advance anti-aging drug development.
The physical and chemical properties of anti-aging drugs significantly impact their pharmacokinetics. CD BioSciences employs advanced techniques to analyze the physical properties of drugs such as particle size, melting and boiling point, density, and refractive index. We help clients assess the solubility of drug candidates in various solvents to predict how they behave in the human body. We also assist in evaluating the drug stability under various conditions to enable clients to determine the shelf-life and viability of formulations.
CD BioSciences supports clients in studying absorption, distribution, metabolism, and excretion (ADME) properties of anti-aging drugs. We specialize in a range of in vitro techniques, including permeability assays and metabolic stability testing, to assess the pharmacokinetic properties of anti-aging drugs. We also offer comprehensive metabolism-related drug-drug interactions (DDIs) analysis services, focusing on key enzyme families such as cytochrome P450 (CYP450) and uridine diphosphate glucuronosyltransferases (UGT).
CD BioSciences provides comprehensive in vivo studies, evaluating the pharmacokinetic parameters of anti-aging drug candidates, such as area under the curve (AUC), peak plasma concentration (Cmax), time to Cmax (Tmax), half-life, and clearance rates. We offer bioavailability studies to assess how the body absorbs and utilizes anti-aging drugs. We also help clients conduct bioequivalence studies to compare the pharmacokinetic profiles of different formulations. We offer tissue distribution studies to reveal how anti-aging drugs interact with target organs and potential sites of action, such as the brain, liver, and skin. We offer specialized assays to evaluate blood-brain-barrier (BBB) permeability using liquid chromatography and mass spectrometry (LC-MS).
Our company offers advanced PK/PD modeling services to analyze anti-aging drugs in various biological systems. By establishing exposure-response relationships, we evaluate how varying concentrations of the drug impact effects over time.
CD BioSciences offers specialized metabolite identification services that employ advanced analytical techniques, such as mass spectrometry and nuclear magnetic resonance (NMR), to characterize drug metabolites. Our experts help clients uncover how anti-aging drugs metabolize in vitro by analyzing microsomal incubations, hepatocyte incubations, S9 fractions, and plasma. We can collect biological fluids such as plasma, urine, and bile from animal models or human subjects. By providing detailed metabolite profiles, CD BioSciences assists in developing safer and more effective anti-aging therapeutics.
At CD BioSciences, our pharmacokinetic services are designed specifically to meet the needs of anti-aging drug development. If you are interested in our services, please feel free to contact usor make an online inquiry.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
