LncRNAs are non-coding RNAs of more than 200 nucleotides in length, which affect a variety of cellular functions through the regulation of gene transcription, post-transcriptional modifications, and epigenetics. LncRNAs appear to be more region-specific in the human aging process, and they have been linked to genomic regulation, cellular function, the aging process, and age-related diseases. Therefore, a better understanding of lncRNA function could help develop new therapeutic approaches to delay aging and treat diseases.
As a global biotechnology company focused on the biology of aging, CD BioSciences is committed to providing high-quality aging-related lncRNA analysis services by combining high-throughput sequencing technology and bioinformatics analysis to comprehensively explore the information of lncRNAs in our clients' samples.
Applications of LncRNAs Analysis in Aging Research
LncRNAs analysis opens up new research possibilities for aging research, including:
- To become a biomarker for identifying aging and diagnosing age-related diseases.
- To discover the regulatory mechanisms between aging-related lncRNAs and mRNAs.
- To analyze known and unknown age-associated transcripts and identify variants.
- To enrich and analyze the function of specific lncRNAs which are with differential or tissue-specific expression.
Our LncRNAs Analysis Solutions
We serve a wide range of researchers in the market for aging biology, including lncRNA discovery, analysis, and related bioinformatics services.
We provide lncRNA sequencing including total RNA detection, library preparation, and sequencing. From RNA samples to data analysis, every step of the way, we ensure data quality for comprehensive and credible bioinformatic analysis.
Data Analysis Process
We perform an overall quality assessment after acquiring the raw data. Reads are compared with the reference genome for data exploration, and the output can be used for cluster analysis and principal component analysis. The transcriptome is assembled and quantified, candidate lncRNAs are screened and expression analysis is performed.
We compare the expression levels of lncRNAs between different age groups (e.g., young vs. old) or healthy vs. diseased states associated with aging, with a focus on lncRNAs that show significant changes in expression associated with aging. We also analyze the correlation between differentially expressed lncRNAs and protein-coding genes to identify potential lncRNA-mediated regulatory mechanisms involved in aging.
Our Advantages
- Provide high-throughput and high-precision sequencing technology with low initial RNA input.
- Flexible solutions for lncRNA identification, quantification, differential expression, enrichment analysis, de novo gene prediction, and target prediction.
- Publishable analysis results to help researchers publish their articles.
CD BioSciences provides customers with simpler and more sensitive transcriptome assays to help them expand the use of lncRNA for applications such as aging retardation and disease treatment. In addition to our lncRNA analysis services, our website also provides a wide range of transcriptome analysis services, technical presentations, and related applications. If you are interested in our services, please feel free to contact us or make an online inquiry.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
