Analysis of the Effects of Environmental Factors on Telomere Length

CD BioSciences offers animal experimental services to study the effects of environmental factors on telomere length. We also support the use of telomere length in the diagnosis and treatment of age-related diseases.

How the Environment Affects Telomere Length and Longevity?

Telomere shortening is a driving factor behind various aging phenotypes. Individuals with shorter telomeres are more susceptible to disease and death. Previous studies have mainly focused on the association between telomere length and aging longevity. Only a few studies have evaluated the relationship between telomere length and environmental factors, as shown in the table below. The findings suggest that certain environmental factors may be associated with telomere shortening and the development of aging.

Our Analysis Services of the Effects of Environmental Factors on Telomere Length

We chose the animal model for aging studies, combining environmental resources, breeding advantages, and laboratory studies to explore the correlation between telomere length and the growth environment of the samples.

• Model selection and environmental exposure. We assist in selecting appropriate animal or cell models for studying aging and telomere length dynamics. Then, we design and implement controlled environmental exposure studies, involving pollutants, temperature variations, or any other relevant factors. We develop detailed protocols for controlled exposure chambers, specialized diet formulations, temperature-controlled environments, or other methods to ensure consistent and targeted exposure.
• Monitoring models. Using environmental sensors or other relevant technologies, we implement monitoring systems to track and measure the actual exposure levels experienced by the animal or cell models. We maintained the experimental subjects under standard conditions and recorded dead individuals daily.
• Telomere measurement and lifespan monitoring. We measure and record the telomere length of individual samples. Moreover, our lifespan monitoring capabilities empower us to track the longitudinal effects of environmental exposures on animal models.
• Statistical analysis of data. By applying rigorous statistical methods, we identify significant associations between environmental factors and telomere length, unraveling the complex interplay of various factors influencing cellular aging processes. In addition, we model to predict the effects of environmental factors on telomere length and individual variability.

Our Advantages

• Abundant materials. Our company provides animal and cell models for studies on senescence, growth environments, and control systems.
• Robust measurement methods. We measure telomere length in individual samples and analyze their distribution to understand the variability of telomere length.
• Accurate statistical analysis. We construct statistical models using informative methods to further analyze the correlation of selection parameters.

At CD BioSciences, our dedicated services for the analysis of environmental factors affecting telomere length provide a valuable resource for advancing scientific understanding in the field of aging and cellular biology. If you are interested in our services, please feel free to contact us.

Reference

1. Reichard M, et al. Lifespan and telomere length variation across populations of wild-derived African killifish. Mol Ecol, 2022, 31 (23): 5979-5992.