Immune profiling refers to the identification and characterization of a person's immune system, including the specific types and quantities of immune cells present. In aging research, immune profiling is often used to understand how immune function changes as people age and to identify potential biomarkers for aging-related diseases. CD BioSciences, a leading company in the field of biological research, offers a comprehensive range of immune profiling services specifically tailored for aging research.
Overview of Our Immune Profiling Services
Immunophenotyping in aging
We provide immunophenotyping in immune profiling, enabling our clients to characterize the distribution and abundance of immune cell subsets with age. By utilizing advanced flow cytometry and mass cytometry (CyTOF) techniques, we can identify and quantify various immune cell subsets, including T cells, B cells, NK cells, monocytes, and dendritic cells, among others. This analysis enables us to determine the composition and dynamics of immune cell populations in individuals of different age groups.
Immune cell functional assays in aging
By examining the functional properties of immune cells from different age groups, we can gain insights into the functional decline or preservation of immune cell subsets with age. We offer a wide range of immune cell functional assays tailored for aging research, including evaluating parameters such as immune cell proliferation, cytokine production, cytotoxicity, phagocytic activity, and antigen presentation.
Longitudinal immune profiling
We offer longitudinal immune profiling services to investigate the dynamic alterations that occur in the immune system as individuals age. By repeatedly analyzing immune cell phenotypes, functional capabilities, and cytokine profiles over time, we can identify patterns and trajectories of immune aging. Longitudinal immune profiling allows for a better understanding of the temporal changes in immune parameters and the identification of potential biomarkers of healthy aging or immune dysfunction.
Immunosenescence assessment
We provide immunosenescence assessment services to evaluate the functional changes that occur in the immune system with aging. We examine markers associated with immune cell exhaustion, senescence-associated secretory phenotype (SASP), impaired immune cell signaling, and altered immune cell activation in response to stimuli.
Our Immune Profiling Techniques
At CD BioSciences, we utilize cutting-edge immune profiling techniques to ensure the high quality and accuracy of our results. Our advanced techniques enable us to capture detailed information about the immune system and its changes with age.
Flow cytometry
We utilize state-of-the-art flow cytometry platforms to perform immunophenotyping and functional assays in aging research, which allows for the simultaneous analysis of multiple parameters at the single-cell level. By combining fluorochrome-labeled antibodies specific to various immune cell markers, we can identify and quantify immune cell subsets with high precision.
Mass cytometry (CyTOF)
We employ CyTOF technology for aging immune profiling, allowing for a more comprehensive analysis of immune cell subsets and functional characteristics. The high-dimensional data generated by CyTOF provides a deeper understanding of the intricate changes occurring in the immune system during aging.
Single-cell RNA sequencing (scRNA-seq)
We also leverage scRNA-seq to study the gene expression profiles of individual immune cells in the context of aging. By analyzing the transcriptomes of thousands of immune cells, we can identify age-related changes in gene expression patterns and uncover novel insights into the molecular mechanisms underlying immune aging.
At CD BioSciences, our comprehensive range of services, including immunophenotyping, immune cell functional assays, longitudinal immune profiling, and immunosenescence assessment, allows for a detailed characterization of the immune system and its changes with age. If you are interested in our services, please feel free to contact us or make an online inquiry.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
