Aging-Related Cardiovascular Disease Research and Drug Development

Aging is a natural biological process that involves a gradual decline in physiological function, including changes in the cardiovascular system. Cardiovascular diseases (CVDs) are a group of disorders that affect the heart and blood vessels, and they represent a significant health concern, particularly in the aging population. The risk of developing CVD increases with age, and aging-related changes in the cardiovascular system can predispose individuals to various conditions.

CD BioSciences offers preclinical contract research services specializing in aging-related CVDs. With years of experience in the industry, our team of highly proficient biological experts is dedicated to providing comprehensive and reliable solutions to our clients.

Aging-Related Cardiovascular Disease Research and Drug Development

Our R&D Services by Type of Aging-Related CVDs

At CD BioSciences, we recognize the importance of understanding the different types of CVDs associated with aging. Our expertise extends to studying prevalent conditions as follows.

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We conduct comprehensive services in the development, progression, and treatment of atherosclerosis. Our services help clients explore novel therapeutic targets and discover drugs to mitigate atherosclerotic plaque formation.

Atherosclerosis

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Our team of scientists helps clients investigate the pathogenesis underlying hypertension development and its impact on cardiovascular health. We help clients discover drugs and evaluate the efficacy of pharmacological interventions in managing hypertension.

Hypertension

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We focus on elucidating the pathophysiology of heart failure and its subtypes. Additionally, we help clients develop innovative therapies, including pharmaceuticals.

Heart failure (HF)

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We provide the molecular and cellular services associated with vascular aging and investigate the impact of aging on vascular function, endothelial health, and arterial stiffness.

Vascular aging

Pathogenic Mechanism Analysis Services for Aging-Related CVDs

CD BioSciences excels in conducting in-depth pathogenesis analysis to unravel the intricate processes involved. Our highly skilled team employs a multidisciplinary approach, incorporating advanced molecular and cellular techniques. By investigating the following key factors, we aim to help clients elucidate the molecular pathways driving aging-related CVDs.

Analysis of arterial stiffness and endothelial dysfunction. We provide advanced imaging services to help our clients investigate how aging affects arterial stiffness and endothelial function, contributing to hypertension and atherosclerosis.
Analysis of metabolic alterations. Using metabolomics platforms, our services cover the study of how aging influences metabolic pathways such as lipid metabolism, glucose homeostasis, and mitochondrial function in the context of CVDs. We also explore the interplay between insulin resistance, dyslipidemia, and obesity in promoting vascular aging and cardiac dysfunction.
Analysis of senescence and cellular aging. Our team of scientists helps clients explore the impact of cellular senescence and telomere shortening on cardiovascular tissues during aging. We assist our clients in investigating how senescent cells contribute to vascular calcification, fibrosis, and impaired myocardial function in aging-related diseases.

Biomarker Identification Services for Aging-Related CVDs

CD BioSciences offers comprehensive biomarker analysis services, employing a wide range of technologies to identify and validate aging-related CVD biomarkers. Our expertise extends to measuring circulating biomarkers in blood samples, assessing tissue-specific biomarkers, and utilizing advanced imaging techniques to evaluate structural and functional changes in the cardiovascular system.

Disease Model Customization Services for Aging-Related CVDs

We specialize in the customization of cell-based and animal models to reflect the specific characteristics of each disease. By tailoring the models to closely resemble human CVDs, we ensure that our clients receive robust and translatable preclinical data, enabling them to make informed decisions regarding drug development and therapeutic interventions.

Drug Discovery and Development Services for Aging-Related CVDs

CD BioSciences is at the forefront of aging-related CVD drug discovery and development. We conduct rigorous efficacy testing using our well-established experiment models, assessing the impact of drugs on disease progression and cardiovascular functions. Furthermore, we perform pharmacokinetic studies to determine the absorption, distribution, metabolism, and excretion of potential drug candidates. Safety assessments are also carried out to evaluate the potential toxicological effects on cardiovascular tissues and other vital organs.

Healthcare R&D Services for Aging-Related CVDs

CD BioSciences recognizes the importance of developing innovative healthcare products that can effectively prevent, diagnose, treat, and manage aging-related CVDs. Through iterative prototyping and rigorous testing, we refine the product design to ensure optimal performance. We also conduct comprehensive preclinical services to assess the safety, efficacy, and feasibility of potential products.

With our extensive expertise in CVDs, CD BioSciences offers our clients a comprehensive suite of services tailored to their specific needs. Our commitment to scientific excellence, meticulous attention to detail, and customer-centric approach make us the ideal partner for advancing research and development in the field of aging-related CVDs. If you are interested in our services, please feel free to contact us or make an online inquiry.