Human aging is an extremely complex biological process that has been explored and studied but still lacks a comprehensive understanding of its mechanisms. The transcriptome is a major determinant of age-related phenotypic diversity, and therefore a systematic analysis of the aging transcriptome can help researchers discover and enrich the mechanisms of molecular changes in aging.
CD BioSciences aims to provide a valuable technical resource for a wide range of aging researchers to capture certain specific changes in the global transcriptome of aging and differential gene expression through a variety of high-throughput transcriptomic technologies.
Introduction of Aging Transcriptomic Profiling
Through studies of the aging transcriptome, we seek to elucidate age-related change pathways and specific responses. For this purpose, we collect mRNA expression data by sequencing technology as well as to fully understand the specific roles of different RNAs, including ncRNAs, miRNAs, circRNAs, tRNAs, and so on, to explore their specific roles in cellular function, gene expression, and so on in aging.
Our Aging Transcriptome Services
Our current service focuses on exploring questions about the molecular mechanisms of aging through RNA sequencing. The sequencing data we provide can help you uncover changes in gene expression and important molecular mechanisms, as well as identify major aging phenotypes at the transcriptional level.
Transcriptome Analysis of Aging
We offer transcriptome analysis as an important tool for studying aging, which can detect age-related transcriptome changes in different age sample species. We can obtain a functional characterization of relevant genes and transcripts by classifying all transcripts, analyzing the variation of expressed genes, and quantifying the levels of transcripts under different conditions.
Transcriptomic Analysis of Cellular Senescence
Cellular senescence is heterogeneous, including its transcriptome characteristics. We provide transcriptome analysis of senescent cells to help clients establish novel anti-aging interventions or therapeutic regimens by detecting and analyzing the transcriptome characteristics of senescent cells.
Transcriptomic Aging Clock Development Services
We provide transcriptome aging clock development services with a combination of biological and computational modeling, which are valuable tools for understanding the aging process, identifying age-related diseases, and evaluating the effectiveness of anti-aging interventions. We can provide research services to accurately predict the biological age of organisms based on transcriptome-defined genomes.
Applications of Aging Transcriptomic Profiling
As one of the leading companies providing research services in the field of senescence histology, we can fully understand and overcome the research challenges you will face and apply our services practically in your project.
- Address the molecular basis of aging through high-throughput and deep RNA sequencing.
- Explore the cell type-specific and tissue-specific changes in aging.
- Obtain transcriptome data related to aging and construct a transcriptome atlas of aging.
- Develop diagnostic and predictive tools for aging and related diseases.
We have a professional team with extensive experimental experience and can provide research solutions for complex aging mechanisms using advanced transcriptomics platforms, including complete transcriptome sequencing plans and data analysis solutions.
CD BioSciences is committed to providing comprehensive aging transcriptome research and application services. If you are interested in our services or have any questions, please feel free to contact us to discuss how we can be involved in your research program.
Reference
- White RR, et al. Comprehensive transcriptional landscape of aging mouse liver. BMC Genomics, 2015.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
