Absolute telomere length has emerged as a prominent biomarker, providing valuable information about cellular aging and lifespan. Absolute telomere length quantification is a technique used to measure the actual length of telomeres in a sample, typically expressed in base pairs. This technique can provide valuable insights into telomere dynamics and their implications in aging, disease, and other biological processes. CD BioSciences offers comprehensive absolute telomere length quantification services for aging studies, providing advanced techniques, customized solutions, and expertise to researchers worldwide.
Overview of Our Absolute Telomere Length Quantification Services
At CD BioSciences, our absolute telomere length quantification services are designed to offer comprehensive, advanced, and tailored solutions for researchers conducting aging studies. In addition to traditional methods of quantitative PCR (qPCR), we offer a range of advanced technologies to ensure accurate and reliable results.
Absolute telomere length quantification by telomere restriction fragment (TRF) analysis
CD BioSciences also offers TRF analysis, a widely recognized technique for telomere length measurement. By utilizing gel electrophoresis to separate DNA fragments based on size, we accurately determine telomere length profiles. Our TRF analysis combines robust protocols and advanced image analysis software to provide detailed quantitative information.
Absolute telomere length (aTL) quantitation PCR
Based on the qPCR technique, we have modified it to determine absolute telomere length. We perform this using a protocol comparable to the initial qPCR determination (T/S ratios based on the amplification of telomeric regions and single-gene regions from separate wells) but with the adaptive length of a standard curve using known telomeres.
Absolute telomere length quantification by fluorescence in situ hybridization (FISH)
We offer FISH-based telomere length quantification, allowing for direct visualization and measurement of telomeres at the individual chromosome level. With our advanced imaging systems and expertise, we provide high-resolution FISH analysis for precise telomere length determination.
Sample Requirements
- Sample types
Blood, saliva, urine, plasma, serum, solid tissue, etc.
- Species
Human. mouse, rats, pigs, etc.
Workflow of Absolute Telomere Length Quantification in Aging Studies
- Sample collection
We collect aging-related samples following standardized protocols. CD BioSciences provides detailed guidelines for proper sample collection to ensure reliable results.
- Absolute telomere length measurement
Using our advanced techniques, we measure the absolute telomere length in the extracted DNA. Each method has its advantages, and our experts guide researchers in selecting the most suitable approach based on their specific study requirements.
- Data analysis and interpretation
CD BioSciences employs advanced algorithms and software for data analysis. We provide comprehensive data interpretation, including statistical analysis and comparison against relevant controls or reference datasets. Our experts extract meaningful insights from the telomere length data, enabling clients to draw accurate conclusions about aging-related processes.
With over years of experience in the field, CD BioSciences consists of highly proficient specialists with extensive knowledge of telomere biology and aging research. We are committed to providing our customers with the latest and most accurate technology for absolute telomere length quantification. If you are interested in our services, please feel free to contact us or make an online inquiry.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
