Polyphenols are a group of naturally occurring compounds found abundantly in plants. The relationship between polyphenols and anti-aging has garnered attention in scientific research due to the compounds' ability to modulate biological pathways associated with longevity. Polyphenols, including resveratrol, curcumin, quercetin, luteolin, and EGCG, possess antioxidant and anti-inflammatory properties that help protect cells from damage, regulate cellular signaling, and promote health at the molecular level.
Fig. 1 Polyphenols exhibit anti-aging effects as senolytics, mitochondrial protectors, anti-inflammatory agents, calorie restriction mimics, autophagy inducers, and antioxidants. (Liu Y, et al., 2024)
CD BioSciences specializes in polyphenol supplement R&D services, developing innovative solutions that target key mechanisms of aging to support longevity and healthy aging.
Resveratrol, a natural polyphenol found in grapes, berries, and peanuts, has gained popularity for its anti-aging properties.CD BioSciences uses advanced extraction and purification methods to obtain concentrated resveratrol, and helps clients develop anti-aging formulations. Moreover, we assist clients in conducting lifespan assays in experimental models to evaluate the effects of resveratrol supplements on oxidative stress, inflammation, and longevity-related pathways.
Our experts use solvent extraction, supercritical fluid extraction, and enzyme-assisted extraction methods to obtain high-purity curcumin. We support clients in evaluating the anti-aging potential of turmeric supplements by measuring aging-related functional responses, including cellular metabolism, autophagy, oxidative stress, and inflammation. In addition, markers associated with mTOR, AMPK, and sirtuin pathways are determined to provide support for observed functional effects and to inform supplement development.
We offer extraction and microbial fermentation to produce high-quality quercetin and provide in vitro and in vivo studies to evaluate the anti-aging potential of quercetin supplements, including assessments of cellular function, oxidative stress, and aging-related biomarkers.
Luteolin helps combat inflammaging and oxidative damage, key drivers of aging-related diseases. Our experts work with various supplement formats, including capsules, tablets, powders, and liquids, to support formulation development and bioavailability assessment. We also conduct detailed in vitro and in vivo studies using experimental models to investigate the effects of luteolin on mitigating inflammaging and oxidative damage.
EGCG is the most abundant catechin in green tea and has been widely studied for its relevance to aging processes. CD BioSciences specializes in the development and evaluation of EGCG supplement formulations, with a focus on assessing their potential anti-aging effects in experimental models.
CD BioSciences offers specialized R&D services for lignan supplements, including extraction and purification methods that ensure high-quality lignan ingredients. We provide in vitro and in vivo studies to evaluate the potential anti-aging effects of lignan supplements, focusing on processes such as oxidative stress, inflammation, and cellular senescence.
There is a growing interest in polyphenol supplements, particularly for their anti-aging properties. CD BioSciences offers a comprehensive suite of R&D services for developing polyphenol supplements, such as resveratrol, curcumin, quercetin, luteolin, EGCG, and lignans, focused on targeting cellular aging, mitigating oxidative stress, and promoting longevity. If you are interested in our services, please feel free to contact us or make an online inquiry.
Reference
- Liu Y, et al. Dietary Polyphenols as Anti-Aging Agents: Targeting the Hallmarks of Aging. Nutrients, 2024, 16 (19): 3305.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
