Hyaluronic acid (HA) is a naturally occurring polysaccharide found in connective tissues, skin, and cartilage. Its unique ability to retain moisture, up to 1000 times its weight, makes it an invaluable ingredient in skincare. With aging, natural HA levels in the skin diminish, leading to moisture loss, reduced elasticity, and the formation of fine lines and wrinkles. Consequently, the incorporation of hyaluronic acid into skincare formulations not only replenishes lost moisture but also enhances skin texture and resilience. Driven by a commitment to scientific excellence, CD BioSciences helps clients develop hyaluronic acid skincare products that meet the growing demand for effective anti-aging solutions.

How Do We Develop Hyaluronic Acid Skincare?
Biosynthesis of hyaluronic acid for anti-aging skincare applications
CD BioSciences employs advanced fermentation techniques using microbial strains that naturally produce hyaluronic acid. We offer purification services for synthesized hyaluronic acid to remove impurities and ensure consistent quality. Our experts support the development of low-molecular-weight hyaluronic acid suitable for deeper skin penetration, promoting long-lasting hydration and collagen synthesis, while high-molecular-weight hyaluronic acid can be incorporated for immediate surface-level hydration.
Formulation development services for anti-aging skincare applications
CD BioSciences specializes in developing innovative hyaluronic acid formulations tailored to address specific skin concerns associated with aging. Our company supports the development of various formulation types, including serums, creams, gels, and masks, each optimized for specific application methods and anti-aging benefits. We also combine hyaluronic acid with other effective actives, such as peptides, vitamins, and antioxidants, to enhance the overall anti-aging efficacy.
Evaluation of the Anti-Aging Efficacy of Hyaluronic Acid Skincare
Hyaluronic acid plays a pivotal role in aging skin by restoring hydration, improving elasticity, stimulating collagen synthesis, and protecting against oxidative damage. At CD BioSciences, we provide comprehensive services to analyze the anti-aging potential of hyaluronic acid in skincare.
- Skin hydration assay tests. Using skin aging models, we measure the moisture retention capabilities of the hyaluronic acid formulations and their efficacy in reducing transepidermal water loss (TEWL) and their efficacy in improving elasticity to evaluate how hyaluronic acid formulations counteract age-related dehydration and skin stiffness.
- Cell renewal efficacy evaluation services. We help clients evaluate the impact of hyaluronic acid skincare on fibroblast activity, collagen synthesis, and keratinocyte renewal. By assessing changes in markers associated with skin regeneration, we help clients analyze the role of hyaluronic acid in promoting skin renewal processes for anti-aging purposes.
- Oxidative stress and inflammation efficacy evaluation. We offer cellular assays to assess the effects of hyaluronic acid skincare on intracellular reactive oxygen species (ROS) levels, cellular resistance to oxidative stress, and inflammatory marker expression relevant to skin aging.
At CD BioSciences, our expertise in biosynthesis, formulation development, and anti-aging efficacy evaluation ensures that we support clients in developing effective hyaluronic acid skincare that meets the demands of the anti-aging skincare market. If you are interested in our services, please feel free to contact us or make an online inquiry.
References
- Papakonstantinou E, et al. Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol, 2012, 4 (3): 253-8.
- Agarwal G, et al. Biosynthesis of Hyaluronic acid polymer: Dissecting the role of sub-structural elements of hyaluronan synthase. Sci Rep, 2019, 9 (1): 12510.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.