Quercetin is a naturally occurring flavonoid found in many fruits, vegetables, and grains, known for its potent antioxidant, anti-inflammatory, and anti-aging properties. It is important in combating oxidative stress and has been studied for its potential benefits in various health conditions. Quercetin is lipophilic, allowing it to cross the blood-brain barrier (BBB) effectively. This ability enables it to exert potential neuroprotective effects, which may help prevent aging-related neurodegenerative diseases.
Fig. 1 Therapeutic application of quercetin in aging-related diseases. (Cui Z, et al., 2022)
CD BioSciences offers a comprehensive range of quercetin supplement R&D services, including extraction, bioproduction, formulation development, and evaluation of anti-aging efficacy.
Overview of Our Quercetin Supplement R&D Services
Quercetin extraction and bioproduction
Using solvent extraction, supercritical fluid extraction (SFE), and microwave-assisted extraction (MAE), we provide advanced extraction and purification services to obtain high-purity quercetin. In addition, we use microbial fermentation with genetically modified yeast or bacteria to produce quercetin from simple sugars or other substrates, optimizing fermentation conditions such as pH, temperature, and nutrient availability to improve yield and consistency.
Formulation development services
Our formulation team specializes in helping clients develop customized quercetin supplements in various forms, such as capsules, tablets, powders, and beverages. Our experts conduct extensive stability studies to evaluate the physical and chemical properties of quercetin formulations over their shelf life, providing data to support product development and quality control.
Preclinical studies
We offer rigorous preclinical studies to evaluate the anti-aging effects of quercetin supplements. Using in vitro and in vivo aging models, we assess the impact of quercetin on cellular senescence, oxidative stress, inflammation, and mitochondrial function, providing clients with insights for developing effective anti-aging supplement formulations.
Applications of Quercetin Supplements in Aging-Related Diseases
- Aging-related neurodegenerative diseases. Quercetin has shown promise in providing neuroprotective benefits, particularly in the context of neurodegenerative conditions such as Alzheimer's and Parkinson's disease. We are committed to providing R&D services to help clients evaluate the impact of quercetin supplements on brain health, including the mitigation of oxidative stress and support of neuronal function.
- Osteoporosis. Quercetin has been shown to promote osteoblast activity, the cells responsible for bone formation. Through our R&D services, we help clients develop quercetin supplements aimed at supporting bone health and protecting against age-related bone loss. Using animal models of osteoporosis, we also help clients assess whether quercetin supplements can enhance bone mineral density (BMD).
- Diabetes. We recognize the potential of quercetin in diabetes care and aim to develop supplements that aid in glucose regulation. We help clients analyze the role of quercetin in modulating glucose transport and metabolism.
By combining scientific rigor with innovative approaches, CD BioSciences helps develop quercetin supplements that target age-related cellular decline, oxidative stress, and chronic inflammation. If you are interested in our services, please feel free to contact us or make an online inquiry.
Reference
- Cui Z, et al. Therapeutic application of quercetin in aging-related diseases: SIRT1 as a potential mechanism. Front Immunol, 2022, 13: 943321.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
