Physicochemical Characterization of Anti-Aging Drugs

Understanding the drug's physical and chemical properties is fundamental in pharmaceutical development. Anti-aging drugs are designed to target various molecular and cellular processes associated with aging. Their physical and chemical properties, such as melting point, solubility, and stability, are integral to their functionality and can significantly influence their performance in preclinical and clinical settings. For anti-aging drugs, these properties are pivotal in determining their efficacy, safety, and overall pharmaceutical quality. CD BioSciences offers various services aimed at helping clients characterize the physical and chemical properties of anti-aging drugs.

Characterization of Physicochemical Properties of Anti-aging Drugs

Characterization of the physical properties of anti-aging drugs

• Particle size distribution. Drug particle size can impact its solubility and bioavailability. We utilize dynamic light scattering (DLS) to determine the size distribution of formulations of anti-aging drugs, including nanoparticle-based systems and other solid-state forms.
• Melting point and boiling point analysis. We help clients determine the melting and boiling points of anti-aging drugs to assess their purity and stability. We utilize advanced capillary methods to determine the melting point. We assist clients in evaluating the thermal behavior of anti-aging drugs under various temperature conditions to determine the boiling point.
• Density measurement. We employ high-precision balances and pycnometers to measure the density of anti-aging drugs of solid and liquid formulations, providing essential data for formulation and process design of anti-aging drugs.
• Refractive index measurement. We help clients measure the refractive index to assess the purity and concentration of active ingredients, which is crucial for ensuring consistency in the formulation of anti-aging drugs.

Characterization of the chemical properties of anti-aging drugs

• Solubility analysis. Solubility is a critical factor affecting the absorption and efficacy of anti-aging drugs. We provide solubility testing to evaluate how well anti-aging drugs dissolve in various solvents. We help clients determine the maximum concentration of an anti-aging drug in different solvents under controlled conditions, providing essential data for formulation development. In addition, we conduct solubility profiling across various pH conditions to simulate physiological conditions.
• Dissolution analysis. We offer dissolution analysis services to measure the rate and extent to which an anti-aging drug dissolves in a specific medium. We simulate gastrointestinal conditions to evaluate how anti-aging drugs dissolve over time, uncovering their absorption potential. We help generate dissolution profiles that illustrate the rate at which an anti-aging drug dissolves, which is vital for understanding its pharmacokinetics.
• Stability analysis. Stability testing is essential for determining the shelf life and long-term efficacy of anti-aging drug candidates. We subject anti-aging drugs to elevated temperature and humidity conditions to evaluate the chemical integrity, potency, and physical properties of formulations. Furthermore, we conduct forced degradation studies under stress conditions, including light exposure, thermal stress, and high humidity, to assess degradation pathways and ensure product robustness under extreme conditions.

Our Tools for Physicochemical Characterization of Anti-Aging Drugs

CD BioSciences leverages a suite of advanced instruments and techniques to deliver reliable data on the physical and chemical properties of anti-aging drugs.

• Differential scanning calorimetry (DSC)
• Thermogravimetric analysis (TGA)
• X-ray powder diffraction (XRPD)
• Fourier transform infrared (FTIR) spectroscopy
• Near-infrared (NIR) spectroscopy
• Ultraviolet-visible absorption spectroscopy (UV/VIS)
• Mass spectrometry (GC-MS, HPLC-MS)

CD BioSciences provides a comprehensive suite of physical and chemical property analysis services to support effective anti-aging drug development. Our rigorous testing methodologies ensure that clients receive reliable data. If you are interested in our services, please feel free to contact us or make an online inquiry.