Zinc is an essential trace element involved in immune function, enzymatic activity, DNA synthesis, and cell division—biological processes that are closely linked to aging-related physiological changes. Age-associated alterations in zinc homeostasis and immune function have driven growing interest in zinc supplementation as a nutritional strategy to support healthy aging and immune resilience in older adults.
Fig. 1 The potential role of zinc as an anti-aging agent in human health and diseases by regulating inflammation, oxidative stress, and DNA damage. (Bao B, et al., 2014)
CD BioSciences provides R&D services to meet the evolving needs of the anti-aging supplement market. For zinc supplements, our capabilities include formulation development, bioavailability studies, and the evaluation of the role of zinc supplements in aging and immunosenescence.
Overview of Our Zinc Supplement R&D Services
Mechanism of action analysis
At CD BioSciences, we provide services to uncover how zinc influences key aging-related pathways. We also help clients explore the role of zinc in modulating signaling cascades, such as NF-κB, p53, and mTOR, which are central regulators of cellular senescence, inflammaging, and longevity.
Formulation development services
Our scientific team specializes in developing zinc supplements for anti-aging applications. We help clients select and optimize suitable zinc forms, such as zinc sulfate, zinc gluconate, zinc citrate, and zinc picolinate, with a focus on their bioavailability and anti-aging efficacy. We also provide customized dosage forms, including tablets, capsules, and liquid formulations, designed to support long-term supplementation in aging populations.
Bioavailability studies
Bioavailability is a critical factor that influences the efficacy of zinc supplements. We offer in vitro and in vivo studies to evaluate how different zinc supplements are absorbed and distributed in aging models. We also help clients assess how zinc supplements interact with other potential anti-aging supplements, with a focus on absorption and bioavailability considerations. For example, we analyze how phytates or certain amino acids impact the bioavailability and anti-aging efficacy of zinc supplements.
Analysis of the Role of Zinc Supplements in Aging and Immunosenescence
Zinc is a critical micronutrient that may influence the biological processes underlying aging. Our company provides comprehensive services to evaluate whether zinc supplements mitigate the progression of age-related changes at the molecular, cellular, and systemic levels. Through both in vitro and in vivo aging studies, we help clients evaluate whether zinc supplements have neuroprotective potential in maintaining cognitive resilience. We support clients in assessing whether zinc supplements can enhance DNA repair mechanisms, reduce genomic instability, and contribute to delaying cellular aging.
Another major focus is on immunosenescence, the progressive decline of immune function with age. We provide advanced immunological assays to assess whether zinc supplements restore immunocompetence in aging models. Furthermore, we analyze the ability of zinc supplements to regulate cytokine expression and inflammatory pathways, which is vital for mitigating inflammaging.
With our extensive expertise, CD BioSciences provides specialized R&D services to support the development and evaluation of zinc-based supplements for anti-aging applications. If you are interested in our services, please feel free to contact us or make an online inquiry.
References
- Cabrera ÁJ. Zinc, aging, and immunosenescence: an overview. Pathobiol Aging Age Relat Dis, 2015, 5: 25592.
- Bao B, et al. The Biological Significance of Zinc in Inflammation and Aging. Inflammation, Advancing Age and Nutrition, 2014, 15-27.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
