The nematode is an organism with simple and rapid genetics. It grows quickly can be kept in the lab conveniently, and is small, so its anatomy and development can be examined easily. And C. elegans is a good model for studying the aging process in an entire organism. For this very useful model, CD BioSciences can provide telomere length test services for common nematode samples, which can provide important clues about how aging occurs and why age-related diseases occur.
Telomere Length in Nematodes
Nematode telomeres are composed of two repeating units TTAGGG and range in length from 8-12 kb. Telomere length is regulated by telomerase, a specialized reverse transcriptase that adds additional TTAGGG repeats to the ends of chromosomes. In nematodes, telomere length is maintained through a combination of telomerase-mediated elongation and end-to-end fusions.
Sample Requirements
CD BioSciences emphasizes the collection of a substantial number of nematodes to achieve statistical significance. Proper sample preservation to prevent DNA degradation is also essential. We recommend fresh nematode samples as optimal (> 1 million cells or >100 µg DNA).
Our Services of Nematode Sample Telomere Length Measurements
CD BioSciences offers a range of services tailored to the precise measurement of telomere length in nematode samples. Our state-of-the-art laboratory facilities and skilled technicians enable the utilization of advanced molecular techniques for accurate telomere length quantification. Our commonly used techniques include quantitative polymerase terminal restriction fragment (TRF), quantitative polymerase chain reaction (qPCR), fluorescent in situ hybridization (FISH), and more!
Our comprehensive services encompass sample processing, telomere length measurement, and in-depth data analysis, providing researchers with valuable insights into nematode genetics and aging. We can also provide specialized DNA extraction services if required for experiments. We provide our clients with data on relative telomere length, average telomere length, shortest telomere length, telomere distribution, and more. The final data contains raw data, images, and an electronic version of the text.
Applications of Nematode Sample Telomere Length Measurements
- Nematodes have a short generation time. Our service can be used to study telomere length regulation across generations.
- Our services can help clients gain a better understanding of the molecular mechanisms underlying aging in nematodes by studying the changes in telomere length over time.
- Our telomere length testing can provide insights into how genetic regulation and gene expression patterns influence telomere maintenance and stability in nematodes.
Our Advantages
- We provide a variety of experimental materials and instruments to meet the experimental needs of different species sample detection.
- We offer professional operators and perfect service systems. We detect the entire follow-up to ensure customer satisfaction.
- We deliver the experimental results and provide after-sales service.
CD BioSciences is dedicated to offering researchers in the field of nematode biology unparalleled expertise and support for telomere length testing. Our services empower researchers to delve into the complexities of nematode agin and genetic regulation. If you are interested in our services, please feel free to contact us.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
