XL765

INQUIRY

CAT. NO.: ABM-021

Product Details
Alternate Name	2-Amino-8-ethyl-4-methyl-6-(lH-pyrazol-5-yl)pyrido[2,3-d]pyrimidin-7(8H)-one; SAR245409
CAS Number	934493-76-2
Molecular Formula	C₁₃H₁₄N₆O
Molecular Weight	270.29
Appearance	White solid
Purity	≥98% by HPLC
Solubility	DMSO
SMILES	CCN1C2=NC(=NC(=C2C=C(C1=O)C3=CC=NN3)C)N
PubChem CID	16123056
Handling	Protect from air and light.
Storage Conditions	-20°C

Description
XL765 is a dual inhibitor of mTOR/PI3K with potential anticancer activities. XL765 inhibits both PI3 kinase and mTOR kinase, which may result in tumor cell apoptosis and growth inhibition in susceptible tumor cell populations. Activation of the PI3K/mTOR pathway promotes cell growth, survival, and resistance to chemotherapy and radiotherapy.

Our customers have direct access to our experts and give timely feedback to any online inquiries. If you are interested in our products, please contact us.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.