U0126

INQUIRY

CAT. NO.: ABS-071

Product Details
Alternate Name	1,4-Diamino-2,3-dicyano-1,4-bis(o-aminophenylmercapto)butadiene
CAS Number	109511-58-2
Molecular Formula	C₁₈H₁₆N₆S₂
Molecular Weight	380.48
Appearance	White to off-white solid
Purity	≥98% by HPLC
Solubility	DMSO (>10 mg/mL)
SMILES	C1=CC=C(C(=C1)N)SC(=C(C#N)C(=C(N)SC2=CC=CC=C2N)C#N)N
PubChem CID	3006531
Handling	Protect from air and light.
Storage Conditions	-20°C

Description
Potent and selective non-competitive inhibitor of MAP kinase kinase(MEK). Inhibits MEK-1 and MEK-2 (IC50 values of 0.07 and 0.06 µM respectively) with little or no effect on the activities of PKC, Abl, Raf, MEKK, ERK, JNK, MKK-3, MKK-4/SEK, MKK-6, Cdk2 or Cdk4.

Our customers have direct access to our experts and give timely feedback to any online inquiries. If you are interested in our products, please contact us.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.