Trichostatin A

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CAT. NO.: ABH-027

Product Details
Alternate Name	TSA, [R-(E,E)]-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
CAS Number	58880-19-6
Molecular Formula	C₁₇H₂₂N₂O₃
Molecular Weight	302.4
Appearance	White solid
Purity	≥99%
Solubility	DMSO (20 mg/mL) or EtOH (2 mg/mL)
SMILES	CC(C=C(C)C=CC(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C
PubChem CID	444732
Handling	Protect from air and moisture.
Storage Conditions	-20°C

Description
Potent, reversible inhibitor of histone deacetylase. Mediates the activation of O6- methylguanine-DNA methyltransferase (MGMT). May be involved in cell cycle progression of several cell types, induces cell growth arrest at both G1 and G2/M phases. In some cases induces apoptosis.

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