Temsirolimus (CCI-779, Torisel)

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CAT. NO.: ABM-018

Product Details
Alternate Name	CCI-779,Torisel
CAS Number	162635-04-3
Molecular Formula	C₅₆H₈₇NO₁₆
Molecular Weight	1030.29
Appearance	White to off-white solid
Purity	≥99%
Solubility	DMSO (200 mg/mL)
SMILES	CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OC(=O)C(C)(CO)CO)C)C)O)OC)C)C)C)OC
PubChem CID	6918289
Handling	Protect from air and moisture.
Storage Conditions	-20°C

Description
mTOR inhibitor with anti-cancer activity. It has anti-angiogenic effects which may contribute to the antitumor activity of temsirolimus observed in breast cancer. Temsirolimus shows synergistic in vivo anti-myeloma effects in combination with dexamethasone in a xenograft model.

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