Methylated DNA Quantification Kit (Fluorometric)

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CAT. NO.: DMK015

General Info
Size	48 tests/96 tests
Product Overview	DNA methylation is a covalent modification of the cytosine ring at the 5' position, resulting in 5-methylcytosine (5-mC). In somatic cells, 5-mC is found almost exclusively in the context of paired symmetrical methylation of the dinucleotide CpG. The biological important of 5-mC as a major epigenetic modification in phenotype and gene expression has been recognized widely. Quantification of 5-mC content or global methylation status in cells such as tumor cells could provide very useful information for detection and analysis of cancer. The Methylated DNA Quantification Kit (Fluorometric) is a complete set of optimized buffers and reagents to quantify global DNA methylation by specifically measuring levels of 5-methylcytosine (5-mC) in a microplate-based format. It can be paired to use with Hydroxymethylated DNA Quantification Kit (Fluorometric), which specifically quantifies 5-hmC, for simultaneously quantification of both methylated and hydroxymethylated DNA.

General Info

Size

48 tests/96 tests

Product Overview

DNA methylation is a covalent modification of the cytosine ring at the 5' position, resulting in 5-methylcytosine (5-mC). In somatic cells, 5-mC is found almost exclusively in the context of paired symmetrical methylation of the dinucleotide CpG. The biological important of 5-mC as a major epigenetic modification in phenotype and gene expression has been recognized widely. Quantification of 5-mC content or global methylation status in cells such as tumor cells could provide very useful information for detection and analysis of cancer.
The Methylated DNA Quantification Kit (Fluorometric) is a complete set of optimized buffers and reagents to quantify global DNA methylation by specifically measuring levels of 5-methylcytosine (5-mC) in a microplate-based format.
It can be paired to use with Hydroxymethylated DNA Quantification Kit (Fluorometric), which specifically quantifies 5-hmC, for simultaneously quantification of both methylated and hydroxymethylated DNA.

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All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.