Isoliquiritigenin

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CAT. NO.: ABA-020

Product Details
Alternate Name	1-(2E,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one; GU 17; ISL
CAS Number	961-29-5
Molecular Formula	C₁₅H₁₂O₄
Molecular Weight	256.26
Appearance	Yellow to orange solid
Purity	≥95% by HPLC
Solubility	DMSO (20 mg/mL)
SMILES	C1=CC(=CC=C1C=CC(=O)C2=C(C=C(C=C2)O)O)O
PubChem CID	638278
Handling	Protect from air and light.
Storage Conditions	-20°C

Description
Isoliquiritigenin (ISL) is a flavonoid found in licorice root and several other plants. Displays antioxidant, anti-inflammatory, and antitumor activities as well as hepatoprotection against steatosis-induced oxidative stress. Acts as a soluble guanylyl cyclase activator. Also displays chemoprevention by induction of phase 2 enzymes such as quinone reductase, that protect cells against reactive, toxic, and potentially carcinogenic species.

Description

Isoliquiritigenin (ISL) is a flavonoid found in licorice root and several other plants. Displays antioxidant, anti-inflammatory, and antitumor activities as well as hepatoprotection against steatosis-induced oxidative stress. Acts as a soluble guanylyl cyclase activator. Also displays chemoprevention by induction of phase 2 enzymes such as quinone reductase, that protect cells against reactive, toxic, and potentially carcinogenic species.

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