FTO, human recombinant

INQUIRY

CAT. NO.: APE-020

Product Details
Size	10 μg
Alternate Name	Fat Mass and Obesity-associated Protein; FATSO.
Gene Symbol	FTO
Gene ID	79068
Source	E. coli
Appearance	Liquid
Physical Form Description	In 0.2 μm-filtered solution in 55 mM Tris-Cl, pH 8.2 containing 150 mM NaCl.
Molecular Weight	65 kDa
Purity by SDS-PAGE	≥90%
Handling	Centrifuge the vial prior to opening.
Storage Conditions	-20°C

Description
FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.

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