Cy5-labeled C-rich telomere probe - 5 nmol

INQUIRY

CAT. NO.: AF005

Product Details
Kits Components	1 x 2mL tube containing 5 nmol of lyophilised probe
Sequence One Letter Code	repeats of CCCTAA
Absorbance (nm)	646
Emission (nm)	662
Modification Position	5'
Conjugation Type	Fluorescent dyes
Conjugation	Conjugated
Form	Dried
Resuspension Condition	Please refer to the protocol
Code Nacres	NA.51

Overview
The sequence of the Cy5-labeled C-rich telomere probe is constituted of CCCTAA repeats and is 5' labeled by the Cy5 fluorescent Dye. The sequence is specific for both human and mouse In principle, fluorescence in situ hybridisation (FISH) should be able to provide information on telomere length of individual chromosomes. However the efficiency of DNA/RNA oligonucleotide hybridizations for telomeric repeats investigation is not sufficient. In comparison the use of PNA stabilizes PNA-DNA/RNA duplexes. When used with PNA probes, PNA-DNA hybridization is much faster within a couple of hours and results in significantly reduced background noise due to the high signal to background noise ratio.

Overview

The sequence of the Cy5-labeled C-rich telomere probe is constituted of CCCTAA repeats and is 5' labeled by the Cy5 fluorescent Dye. The sequence is specific for both human and mouse
In principle, fluorescence in situ hybridisation (FISH) should be able to provide information on telomere length of individual chromosomes. However the efficiency of DNA/RNA oligonucleotide hybridizations for telomeric repeats investigation is not sufficient. In comparison the use of PNA stabilizes PNA-DNA/RNA duplexes. When used with PNA probes, PNA-DNA hybridization is much faster within a couple of hours and results in significantly reduced background noise due to the high signal to background noise ratio.

Our customers have direct access to our experts and give timely feedback to any online inquiries. If you are interested in our products, please contact us.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.