BMP-3b/GDF-10, human recombinant

INQUIRY

CAT. NO.: APE-008

Product Details
Size	100 μg
Alternate Name	BMP-3b, BMP3B, BIP, Growth differentiation factor 10
Gene Symbol	GDF10
Gene ID	2662
Source	E. coli
Appearance	Liquid
Physical Form Description	In 10 mM sodium citrate (pH 3.5) containing 10% glycerol
Molecular Weight	12.5 kDa
Purity by SDS-PAGE	≥95%
Amino Acid Sequence	MQWDEPRVCS RRYLKVDFAD IGWNEWIISP KSFDAYYCAG ACEFPMPKIV RPSNHATIQS IVRAVGIIPG IPEPCCVPDK MNSLGVLFLD ENRNVVLKVY PNMSVDTCAC R
Handling	Centrifuge the vial prior to opening.
Storage Conditions	-80°C

Description
GDF10 (Growth differentiation factor 10) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It is expressed in femur, brain, lung, skeletal, muscle, pancreas and testis, and it plays a role in head formation and may have multiple roles in skeletal morphogenesis. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Recombinant GDF10 protein was expressed in E. Coliand purified by using conventional chromatography techniques.

Description

GDF10 (Growth differentiation factor 10) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It is expressed in femur, brain, lung, skeletal, muscle, pancreas and testis, and it plays a role in head formation and may have multiple roles in skeletal morphogenesis. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Recombinant GDF10 protein was expressed in E. Coliand purified by using conventional chromatography techniques.

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