Apolipoprotein AII, human plasma

INQUIRY

CAT. NO.: APE-003

Product Details
Size	500 μg
Alternate Name	Apolipoprotein A-II, Apo-AII, ApoA-II, APOA2.
Gene Symbol	ApoA2
Gene ID	336
Source	Human plasma.
Appearance	Frozen
Physical Form Description	Frozen in 10 mM NH4HCO3, pH 7.4
Molecular Weight	17.4 kDa
Purity by SDS-PAGE	≥ 95%
Handling	Centrifuge the vial prior to opening.
Storage Conditions	-80°C

Description
APOA2 stabilizes the HDL structure by its relationship with lipids, and plays a role in the HDL metabolism. APOA2 is the 2nd most abundant protein of the high density lipoprotein particles. 25% of Apo A in HDL is Apo AII. APOA2 is localized in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in APOA2 gene might cause apolipoprotein A-II deficiency or hypercholesterolemia. Levels of Apo AII in normal plasma range from 30-50 mg per 100 ml. The physiological role of the protein is unknown. Alcohol consumption, however, increases Apo AII levels.

Description

APOA2 stabilizes the HDL structure by its relationship with lipids, and plays a role in the HDL metabolism. APOA2 is the 2nd most abundant protein of the high density lipoprotein particles. 25% of Apo A in HDL is Apo AII. APOA2 is localized in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in APOA2 gene might cause apolipoprotein A-II deficiency or hypercholesterolemia. Levels of Apo AII in normal plasma range from 30-50 mg per 100 ml. The physiological role of the protein is unknown. Alcohol consumption, however, increases Apo AII levels.

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