Allicin

INQUIRY

CAT. NO.: ABA-003

Product Details
Alternate Name	3-prop-2-enylsulfinylsulfanylprop-1-ene; 2-propene-1-sulfinothioic acid, S-2-propen-1-yl ester; S-allyl prop-2-ene-1-sulfinothioate
CAS Number	539-86-6
Molecular Formula	C₆H₁₀OS₂
Molecular Weight	162.27
Appearance	Oil
Purity	≥98%
Solubility	Soluble in Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone
SMILES	C=CCSS(=O)CC=C
PubChem CID	65036
Handling	Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions	-80 ºC

Description
Allicin is a natural product isolated from garlic (Allium sativum) that exhibits many biological effects including antioxidative, anticancer, antimicrobial, and antifungal activities. Allicin (5-10 µM) dose-dependently inhibits cell adhesion, invasion, and migration in lung adenocarcinoma cell lines A549 and H1299. It also alters the balance of tissue inhibitors of matrix metalloproteinases (TIMPs) and matrix metalloproteinases (MMPs), decreases phosphorylation of Akt, and decreases PI3K/Akt signaling.

Description

Allicin is a natural product isolated from garlic (Allium sativum) that exhibits many biological effects including antioxidative, anticancer, antimicrobial, and antifungal activities. Allicin (5-10 µM) dose-dependently inhibits cell adhesion, invasion, and migration in lung adenocarcinoma cell lines A549 and H1299. It also alters the balance of tissue inhibitors of matrix metalloproteinases (TIMPs) and matrix metalloproteinases (MMPs), decreases phosphorylation of Akt, and decreases PI3K/Akt signaling.

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