Characterization of Social Aging in Animal Models
Experimental Models
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Characterization of Social Aging in Animal Models

Aging is associated with a wide range of behavioral changes. Social behavior analysis helps researchers to identify and characterize these changes, providing a deeper understanding of how aging impacts social interactions and relationships. Analyzing social behavior in aging models helps researchers to elucidate how the social context affects the aging process, including longevity and quality of life.

Mice social behaviors

CD BioSciences provides a suite of services designed to analyze social behaviors in animal models, with a focus on aging-related changes. Our services include both social interaction tests and the intruder-resident paradigm, enabling clients to explore the complex dynamics of social behavior and how they change with aging.

Characterization of Social Aging by Behavior Analysis

Characterization of Social Aging Using Social Interaction Tests

Our platform is equipped with advanced techniques to analyze and quantify various aspects of social behavior in animal models, including social preference, interaction, and novelty recognition. We help clients prepare the apparatus for social interaction testing, which consists of a rectangular box with three chambers. Behavioral metrics such as time spent near a conspecific, as well as the frequency and duration of specific behaviors (e.g., sniffing, following, allogrooming, mounting, biting, wrestling), are recorded. Leveraging data analysis algorithms, we can provide clients with a detailed assessment of social tendencies and how they change with aging.

Characterization of Social Aging Using Intruder-Resident Paradigm

Our intruder-resident paradigm services are designed to investigate age-related changes in social dynamics. In this test, an unfamiliar intruder is introduced into the territory of a resident animal, and responses such as aggression, avoidance, and exploratory behaviors are closely monitored. By comparing the behavioral patterns of younger and older animals, we help clients uncover the neurobiological and hormonal mechanisms underlying social behavior changes during aging.

Applications of Social Behavior Analysis in Aging Research

  • Evaluating anti-aging therapeutics. We provide preclinical social behavior analysis services to help clients determine the potential of anti-aging therapeutics to improve social functioning in the elderly.
  • Identifying age-related behavioral phenotypes. Social behavior analysis can identify specific behavioral phenotypes associated with aging. We support clients in tracking the onset and progression of aging-related diseases and assessing the efficacy of therapeutic interventions.
  • Investigating the role of social interactions in healthy aging. Using animal models, our clients can observe how social interactions contribute to overall health and longevity. We help design studies and analyze data to inform anti-aging therapeutics that promote social engagement among the elderly.

At CD BioSciences, we are proud to offer services to characterize social aging in animal models. Our team of skilled specialists and advanced technology ensures that our clients receive comprehensive and reliable data to advance their research goals. If you are interested in our services, please feel free to contact us or make an online inquiry.

Reference

  1. Ana PV and Fariñas I. Behavioral evaluation of aging in experimental animals. Assessments, Treatments, and Modeling in Aging and Neurological Disease, 2021, 553-564.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.