Deferoxamine Mesylate

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CAT. NO.: ABA-009

Product Details
Alternate Name	DFOM, Deferoxamine methanesulfonate salt, Desferrioxamine mesylate salt
CAS Number	138-14-7
Molecular Formula	C₂₅H₄₈N₆O₈·CH₄O₃S
Molecular Weight	656.79
Appearance	White to off-white solid
Purity	≥98% by HPLC
Solubility	H₂O ( 50 mg/mL)
SMILES	CC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCN)O)O)O.CS(=O)(=O)O
PubChem CID	62881
Handling	Protect from air and moisture.
Storage Conditions	-20°C

Description
An iron chelator used for the treatment of acute iron intoxication and of chronic iron overload due to transfusion-dependent anemias. Has been shown to have anti-proliferative effects on vascular smooth muscle cells in vitro and in vivo and to arrest cells in the G1 phase. Induces apoptosis in HL-60 cells by chelating iron. In addition, it has been shown to have antioxidant properties and to protect cells against H₂O₂-induced damage.

Description

An iron chelator used for the treatment of acute iron intoxication and of chronic iron overload due to transfusion-dependent anemias. Has been shown to have anti-proliferative effects on vascular smooth muscle cells in vitro and in vivo and to arrest cells in the G1 phase. Induces apoptosis in HL-60 cells by chelating iron. In addition, it has been shown to have antioxidant properties and to protect cells against H₂O₂-induced damage.

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