It has been shown that miRNA expression changes dramatically during human aging. In some cases, age-related changes in miRNA expression appear to have a protective effect against divine aging. CD BioSciences has been providing aging-related transcriptome analysis services, and our experts have extensive experience and unique insights in analyzing RNA datasets. To support the growing research interest in aging-related microRNAs, we provide microRNA sequencing services including novel microRNA discovery, expression and characterization.

Introduction to Age-Dependent MicroRNAs

MicroRNAs are small non-coding RNA molecules that play an important role in regulating gene expression by interacting with transcripts and reducing the abundance of mRNAs or proteins to control a wide range of cellular processes including the aging process.

As researchers discover new microRNAs and uncover their regulatory and protective mechanisms associated with human aging, it becomes possible to use them as key regulators of aging for anti-aging drug development or disease therapy development.

Comprehensive MicroRNAs Analysis Services We Offer

We provide a rapid, one-stop microRNA sequencing analysis service based on the samples you provide through sequencing technology and data analysis.

• For a wide range of species. Target population Includes samples of any species that can be analyzed for their age-related microRNAs.
• For whole transcriptome range. We can analyze known or unknown RNAs within the transcriptome of the study sample.
• For transcriptome data. We detect new or mutated transcripts, enabling qualitative and quantitative transcript expression analysis.

These comprehensive services are designed to provide a one-stop shop for RNA analysis and produce the results needed to rapidly advance your aging-related biological or medical research. You can discover new miRNAs and examine the differential expression of all miRNAs in any sample by using our services.

Service Processes

Service Options		Descriptions
	Sample Preparation	Total RNA amount ≥ 5 µg Concentration ≥ 200 ng/µl All RNA samples you submit will be verified for purity and quantity.
	Sequencing	Build miRNA libraries with customizable size selection support. ≥ 7~10 M reads
	Data Analysis	Sequencing data enrichment and functional annotation. Expression analysis, length distribution, transcript copy comparison. Optional miRNA target prediction.

Our Advantages

• Identify additional unmapped microRNAs and biomarkers of aging or related diseases.
• Powerful sensitivity and dynamic range for a wide range of detections.
• Study and characterize microRNA function and predict potential microRNA target molecules without the need for a usable reference genome.
• The latest next-generation sequencing technology and an experienced team.
• Complete bioinformatics analysis with expert technical support to assist in data interpretation.

CD BioSciences has completed many microRNA detection and analysis projects, and our team has accumulated a deep understanding of our customers' requirements. With our extensive experience and technical support, we are committed to helping our clients design and advance your aging-related microRNA research program.

We provide one-stop sequencing services including sample preparation, library preparation, deep sequencing, data quality control, data analysis, and can customize specific analysis routes based on your research interests. If you have additional requirements or questions, please feel free to contact us.

Reference

1. Ham S and Lee S. Advances in transcriptome analysis of human brain aging. Experimental and Molecular Medicine, 2020, 52(11):1787-1797.

Our services are for research use only and not for any clinical use.