DNA Methylation Age Acceleration Research


DNA methylation levels are age-dependent and can vary over time. When an individual's DNA methylation age is greater than the actual age, this means that the individual is in an age acceleration state, and which may be associated with many aging manifestations, disease development, and even death. CD BioSciences can provide research services related to age acceleration to help researchers explore its association with the aging performance, age-related diseases, and even death.

DNA Methylation Age Acceleration

Age acceleration can be defined as the difference between the DNA methylation age and the actual age, or as the residual resulting from regressing the DNA methylation age on the actual age. In comparison, the latter definition is more accurate and practical. We can determine the rate of biological aging based on the specific value of the DNA methylation age acceleration, with positive values indicating faster than expected aging and negative values the opposite.

DNA methylation age acceleration is closely related to the health status of the organism, aging-related diseases, mortality and other factors. On the one hand, several studies have identified DNA methylation age acceleration in age-related diseases, such as cancer, cardiovascular diseases, and neurodegenerative diseases. On the other hand, there are also some intrinsic and extrinsic factors that contribute to age acceleration in individuals, such as stress, alcohol consumption, smoking, etc.

Our Services

Our service focuses on studies that explore the specific relationship between biological age acceleration and various age-related realizations.

Genome-wide DNA methylation analysis

Genome-wide DNA methylation analysis

We perform genome-wide DNA methylation analysis, as well as data quality control, on blood samples or other tissue samples from large study populations.

Age acceleration calculation

Age acceleration calculation

we calculate the DNA methylation age acceleration by regression model and submit the processed DNA methylation data to obtain the age acceleration values.

Relevance statistical analysis

Relevance statistical analysis

We build multiple models to assess the relationship between DNA methylation age acceleration and various aging phenotypes such as health, disease, and death.

Our services address a wide range of studies, including studies of the association between age acceleration and some aging phenotypes, as well as studies of how various internal and external factors affect age acceleration. Specific services can be viewed by clicking on the links.

Delivered Reports

We can provide the following types of studies depending on your research needs

  • Report on the analysis of age-related diseases, their influencing factors and age acceleration.
  • Report on the analysis of external influences and age acceleration.
  • Report on the analysis of genetic factors and age acceleration.

CD BioSciences has a comprehensive DNA methylation technology platform to support the technical needs of the aging and related disease research process and to provide you with a high level of professional experience and quality service. If you are interested in our services, please feel free to contact us for any of your related needs.

Our services are for research use only and not for any clinical use.

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We are a comprehensive technology platform company integrating aging DNA methylation, telomere, transcriptome, proteome, and metabolome research.

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