Cell Reprogramming Therapy to Reverse Aging
InquiryWith aging, we continue to age and are often at risk for cardiovascular disease and cancer. In order to slow down aging and address age-related diseases, many scientists have now discovered that we can safely and effectively reverse the aging process by resetting older cells to a more youthful cellular state. This cellular approach can not only reverse aging and address age-related diseases, but also restore tissue and body health in different diseases by improving cellular function.
CD BioSciences can assist scientists and pharmaceutical companies in the field of aging research, and we provide research on cellular regenerative therapies for reversing aging, fully supporting our clients' projects from development, evaluation to validation using advanced technological approaches and research facilities.
Advanced Cell Programming Technologies
- Induced Pluripotent Stem Cell (iPSC) Technology
iPSC technology is the transformation of somatic cells into induced pluripotent stem cells that can reverse age-related changes. Somatic cell reprogramming can be achieved by somatic cell nuclear transplantation, transcription factor induction, cell fusion, and cytoplasmic incubation, and the target cells will be transformed into totipotent cells to improve tissue function to reverse aging.
- Cell Reprogramming Technology
Reprogram specific genes of senescent cells to make them biologically younger while retaining their own functions and properties.
Fig 1. iPSC technology (Hockemeyer
D and Jaenisch R, 2016)
Our Services
Human aging is often accompanied by the onset of metabolic disorders, neurodegenerative diseases, skin wrinkles, and an increased risk of aging-related diseases. In our service, we hope to help researchers and biopharmaceutical companies develop therapies to reverse aging through cellular programming techniques designed to make older cells more resistant to injury and disease by allowing them to regain the functions and properties of younger cells.
Reprogramming factors
Reprogramming factors are commonly added to cells in cellular reprogramming to reset the cellular epigenetic markers to their original pattern or to a young state. Yamanaka factors, Oct4, Sox2, Klf4 and cMyc are widely used in cell therapy to induce them into stem cells. For specific cells, we develop programming factors by analyzing specific molecules and genes.
Animal model experiments
We can use different animal models of aging to verify the effectiveness of cellular therapies, to observe the ability to recover cellular functions and the recovery of aging tissues and organismal health, and to assess the aging of individuals by various aging clocks.
Applications
- Anti-aging drug development
- Development of therapies for age-related diseases
- Regenerative medicine therapy development
- Other therapeutic applications
We may be able to use cellular regeneration throughout the life cycle to slow down aging in normal animals and even in humans, and through our research services may be able to bring you valuable discoveries that could lead to the development of a promising anti-aging direction.
In order to investigate reliable cellular programming to reverse aging, CD BioSciences offers you more possible technical approaches and research protocols. If you have a precise project plan or research protocol, you can contact us to help you execute it quickly.
References
- Han M J, et al. Inhibition of neural stem cell aging through the transient induction of reprogramming factors. Journal of Comparative Neurology, 2020.
- Hockemeyer D and Jaenisch R. Induced Pluripotent Stem Cells Meet Genome Editing. Cell Stem Cell, 2016, 18(5):573-586.
Our services are for research use only and not for any clinical use.
Online Inquiry
We are a comprehensive technology platform company integrating aging DNA methylation, telomere, transcriptome, proteome, and metabolome research.