Although the specific mechanisms of human aging are still not fully explored, whole-transcriptome sequencing provides a wide range of transcriptome analysis to aid in-depth analysis of aging-related gene expression. CD BioSciences provides transcriptome sequencing services tailored to your research objectives for your aging samples, including a one-stop sequencing service from sample preparation to data analysis, enabling rapid analysis and insight into the RNA of your target subjects.

What is Whole Transcriptome Sequencing?

It is an important tool for addressing the molecular mechanisms of biological and medical problems, which can reveal the presence and amount of RNA in biological samples. Whole transcriptome sequencing analysis can include the analysis of coding and non-coding RNAs such as mRNA, lncRNA, miRNA, circRNA for a comprehensive transcriptional regulatory networks analysis.

Therefore, the whole transcriptome sequencing of aging can help our understanding of all transcriptional activities associated with aging, can demonstrate the dynamics of RNA with age at different genomic levels, and offers the possibility of age-associated RNA gene candidate discovery.

Our Services

We provide a full suite of transcriptome sequencing services for aging research, including library preparation, high-throughput sequencing and bioinformatics analysis. To gain a comprehensive understanding of aging-related mechanisms, our researchers can obtain high-quality aging analysis services through whole-transcriptome sequencing.

After you submit your samples, we will help you with sample quality control to ensure that the samples meet technical standards. Following our service process, RNA libraries, both coding and non-coding, are prepared based on your target organisms, followed by sequencing with the appropriate sequencing instrument and sequencing system, with all sequencing reagents provided by us on a custom basis. The final result data will be quality controlled for quality assurance and bioinformatically analyzed to provide publishable results.

Sample Requirements

Sample types	Amount	Concentration	Storage
Total RNA (Acceptable for blood, cells, tissues)	≥5 mg	≥20 ug/uL	RNA should be stored in nuclease-free water or RNA stabilization solution.

Advantages

• Allows for non-coding RNA and splice variant detection/comparison across phenotypes.
• Ability to quantify entire gene levels or to quantify individual transcripts.
• The detection range and sensitivity can help find more of the data being sought.
• Multiple sample types suitable, fast turnaround time, high quality sequencing data.
• Low cost and best-in-class technology level.

Whole Transcriptome Sequencing Applications in Aging Research

• Analyze mRNA, ncRNA, miRNA in a single sequencing to explore the regulatory elements associated with aging.
• Decipher the role of RNA in aging and discover relevant RNA mechanisms can help develop anti-aging drugs or treat related diseases.

Whole transcriptome sequencing is very important to understand the expression of aging genes and the mechanisms of related diseases. As one of the few professional aging research service providers, CD BioSciences provides one-stop aging transcriptome sequencing services with years of service experience and technology platform.

If you have any questions or interest in our senescence whole transcriptome sequencing services. Please contact us for more information and a detailed quote.

Reference

1. Kukurba K R and Montgomery S B. RNA Sequencing and Analysis. Cold Spring Harbor Protocols, 2015, 2015(11):951.

Our services are for research use only and not for any clinical use.