Aging Proteome Analysis

Proteins and metabolites are the end products responsible for setting the phenotype of aging, proteins can influence physiological functions as well as provide clues to the mechanisms of aging, therefore we should provide more information resources on proteomics for the study of aging and age-related diseases.

Proteomics platforms are capable of assessing various proteins from a wide range of biological samples. Proteomics studies allow the identification of protein classes in different tissues and the characterization of changes in protein expression to provide insight into aging mechanisms and to be used as biomarkers to monitor the aging process of the body. This new source of aging information also offers the possibility of lifespan extension and development of disease therapies.

To address proteomic research in aging, CD BioSciences provides quantitative analysis of aging proteins to give researchers direct information about the biological pathways of aging.

Aging Proteome Quantification Analysis

We use LC-MS/MS technology to provide of proteome analysis of numerous biological samples to obtain a comprehensive proteomic data set. Clients can use such a valuable information resource to understand and elucidate the molecular pathways of aging and related diseases.

The generic operational flow of our analytical method is shown in the figure below and can be used for large-scale quantitative proteomics.

• Sample processing. Mainly includes sample homogenization and protein digestion processing.
• MS analysis. The treated samples are separated in a graded manner, eluted on the sample, and scanned for quantification.
• Data analysis. We provide pre-processing of raw sequencing data, mass spectrometry searches in the proteomic database, functional annotation, enrichment analysis and clustering analysis of age-related proteins, etc.

Our Unique Advantages

We provide research services based on transcriptome analysis of aging.

Applications of Aging Proteome Quantification

We provide comprehensive proteomic data that can be used as a valuable resource for a variety of aging research efforts, including but not limited to,

• It can provide a reference for determining whether the target protein is expressed and the expression level.
• It can provide protein co-expression network analysis that correlates protein modules with aging or related diseases to elucidate their link to diagnosis.

As one of the technical service providers for aging research, CD BioSciences utilizes an advanced proteomic platform to build services and provide solutions for your aging research. We take care of all aspects of the project, including sample processing, mass spectrometry and bioinformatics analysis.

You just need to tell us your experimental purpose and send relevant experimental samples and will get one-stop service. If you have any questions, please fill out the inquiry form and contact us immediately.

Reference

1. Ping, L, et al. Global quantitative analysis of the human brain proteome in Alzheimer's and Parkinson's Disease. Sci Data 5, 2018, 180036.

Our services are for research use only and not for any clinical use.