The DNA methylation model is an important tool for assessing the actual age and health and aging status of a sample. It is worth noting that tissue-specific DNA methylation predictor may have better accuracy. As the largest organ of the human body, the skin tissue provides a more comprehensive age analysis method based on DNA methylation analysis. And specific skin tissue age prediction model can be used as an important tool for analyzing human skin health and aging and the discovery of novel compounds capable of altering the age of DNA methylation. CD BioSciences can provide age prediction services for skin tissue samples. We collect and process DNA methylation data obtained from human skin samples to build skin tissue-specific DNA methylation age prediction models to help customers predict individuals with high accuracy biological age.

Our Services

• DNA methylation model building service. We analyze genome-wide methylation data from specific datasets of dermis, epidermis, whole skin tissue, as well as analyze samples for tissue of origin, sex, and chronological age. Data are combined and processed to build models.
• Age predictive analysis. We perform DNA sample collection and methylation analysis on the provided samples, and perform statistical analysis on the test data. The predicted age can be used to analyze human skin health and aging.

Skin-Specific DNA Methylation Clock Technology

we discover and select different CpG sites to construct DNA methylation models, and compare and obtain highly specific and accurate age prediction models for skin samples, which is highly correlated with age and can obtain high precision results. We can obtain total DNA samples from cultured cells or human skin biopsies and perform paired tests on the provided samples to obtain predicted age.

Applications

• Study the effect of different aging treatments on DNA methylation age of skin. Our skin-specific clock service can help customers achieve accurate prediction of skin DNA methylation age and calculate the impact of different aging interventions on it.
• Predict age-related changes in DNA methylation due to disease. We provide powerful tools for understanding skin diseases and how they affect overall body health.
• Predict treatment effect. Our services allow you to research and validate the effects of novel compounds for skin treatment and interventions to modulate skin aging.

Advantages

We have rich experience in DNA methylation clock development, a professional technology platform, and a dedicated team of experts. We can provide you with skin tissue-specific DNA methylation age prediction services, including one-stop service for development and detection, to accelerate your skin health and aging research process.

CD BioSciences is committed to using superior technology to develop specific DNA methylation clocks for different tissues. We provide the best service to help clients develop and apply DNA methylation analysis technology at the most competitive cost. Please contact us for more information and a detailed quote.

Reference

1. Boroni M, et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics, 2020, 12(1).

Our services are for research use only and not for any clinical use.