DNA Methylation Age Prediction for Saliva
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DNA Methylation Age Prediction for Saliva


Most DNA methylation age clocks on the market today are models for blood samples, but saliva is also a common body fluid, and its DNA methylation pattern can also be used as a biomarker of aging. Saliva contains DNA methylation at some highly predicted CpG sites, which may provide the potential for highly accurate age prediction. As a service provider for aging research, CD BioSciences can provide professional support for DNA methylation analysis of various tissues and body fluids to customers worldwide.

Age Prediction Model for Saliva

With the continuous development of technology, several tissue-based models of DNA methylation have been generated in the field of epigenetics, and age-related CpG sites can be identified and applied, and some tissue-specific age prediction models have been constructed. Among them, the DNA methylation age prediction model based on saliva samples has specific CpG site markers, it is precisely because the saliva samples have a heterogeneous cellular composition, including oral epithelial cells and leukocytes, which enables the model to provide high predictive accuracy.

Our Services

CD BioSciences provides an age prediction service based on saliva samples, which analyzes the methylation status of the saliva genome through DNA methylation clocks and predicts the actual age of the samples. We develop and validate age prediction models, reducing customer analysis cost and time, providing cost-effective and potentially useful methods in the field of predicting age.

Saliva Age Prediction Service Based on DNA Methylation Analysis

Data and material collection

  • Collection and sequencing of saliva samples from volunteers of a wide range of ages
  • Data access to public databases

Model building

  • Data collection and processing
  • DNA methylation analysis of CpG sites
  • Regression model construction

Age prediction

  • Saliva sample collection
  • Genome-wide DNA methylation analysis
  • Statistical measurement

Data and Materials

All sample materials are collected for research with permission from the Ethics Committee, and all experiments are conducted in accordance with the ethical guidelines for genetic research. We protect the confidentiality of personal data we access, and the confidentiality of related data obtained during research.


The age prediction model of saliva samples we provide can be applied in practical research, including but not limited to:

  • Accurate prediction of age of collected samples
  • Research on extending human lifespan
  • Forensic lab work

CD BioSciences is a service provider for aging and longevity research, providing a comprehensive and extensive biological age clock technology platform, our innovative technology can be your ideal collaboration platform. Our specialized DNA methylation analysis technology provides individuals, research institutions, governments or companies with a wide range of service options, including innovative technology platforms, predictive modeling tools and fast service cycles.

Please contact us for the service you need, you can contact us via hotline or email. We will respond to your questions and requests within 24 hours.


  1. Hong S R, et al. DNA methylation-based age prediction from saliva: High age predictability by combination of 7 CpG markers. Forensic Sci Int Genet, 2017, 29:118-125.
  2. Hamano Y, et al. Forensic age prediction for saliva samples using methylation-sensitive high resolution melting: exploratory application for cigarette butts. Rep, 2017, 7(1):10444.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.